ABSTRACT
Cardiovascular disease (CVD) is the sixth mos common human disease that causes about 17.3 million deaths yearly Advancement in nanomedicine enables the usage of nanomaterials fo treating cardiac disorders. Among these, Cerium Oxide (CeO2 nanoparticle is gaining attention due to their irreversible oxidativ states (Ce3+ and Ce4+), which provide them with many unique physiologically important traits like antioxidant property, Anti inflammatory property, free radicle scavenging potential etc. All thes features make CeO2 an excellent agent for treating many cardia related disorders. We have used the search engines PubMed an Google scholar to identify the relevant papers in last 5 years on thi topic. Some old classical articles were also identified, and the review was written based on these relevant papers. Cerium nanoparticle (CeNPs) are being used in the therapy of CVD mainly for reducin oxidative stress, inflammation, and damage caused by free radicals CeO2 can also protect endothelial cells (ECs) from apoptosis. It can b used as a wound-healing agent during cardiac surgeries. This i because of its potential to enhance endothelialization. In this article we reviewed various applications of CeO2 in the field of CVD.Copyright © 2023 Society of Pharmaceutical Sciences and Research. All rights reserved.